Exosomes are cell-derived vesicles that bring growth factors, signaling proteins, and lipids from A to Z, helping facilitate important repair and regeneration processes beyond the depth of most surface-level treatments. It’s no wonder more and more people are wondering how to use exosomes in skincare.
We’ve put together this quick guide to help you understand the potential of our exosome skin care products and make the most of them in your ritual. Naturopathica’s Gotu Kola and fruit-based Exosome formulas can support aging, stressed skin and help restore a smoother, firmer skin. Learn more below.
Key Takeaways
- Exosomes support repair, hydration, and firmness at the cellular level deep within the skin.
- Topical Exosomes are a safer and more economical way to reap the benefits of these cell-derived vesicles compared to injectable Exosomes.
- Apply an Exosome toner on damp skin after cleansing, then follow with an Exosome moisturizer to seal in the active compounds.
- Consistency is everything. Stick with your ritual for at least 4-6 weeks to see the full potential these clinically proven products have to offer.
What Do Exosomes Do?
You might be somewhat familiar with the power of Exosomes in skincare if you’re here looking for tips on adding them to your regimen. But few people are aware of just how many different skin concerns they can help with.
How They Work
First things first. What is an Exosome in skincare? These membrane-bound vesicles are naturally released by cells throughout your body. You can supplement them through skincare, though.
They’re little delivery vehicles, tasked with bringing growth factors, antioxidants, and signaling proteins from one cell to another. They essentially tell recipient cells how to repair, regenerate, and protect. These are things your skin already knows how to do, but sometimes starts to do at a lower rate of efficiency. This is when slower skin turnover, fine lines, uneven tone, and other concerns start to pop up.
New York-based dermatologist Dr. Doris Day has extensively studied Exosomes and is passionate about what they can do. “Exosomes are simply messengers. They are released from stem cells and naturally attracted to areas of inflammation. They carry growth factors and other anti-inflammatory, immune-supportive and antioxidant elements to places that need them.”1
What Can They Do?
Here are just a few of the many reasons you should learn how to use Exosomes in skincare:
- Restoring cellular communication: A lot of the signs of aging can be traced back to signaling pathways becoming less clear over the years. Exosomes help restore these communication networks. Board-certified dermatologist Dr. Mona Gohara describes them as "a high-tech signaling system that coordinates skin regeneration.”2
- Hydration and moisture retention: The growth factors delivered by Exosomes can support your skin’s ability to keep water locked in where it’s needed. You get deeper hydration than a surface-level humectant could ever achieve.
- Firmness and texture: Exosomes can breathe fresh life into skin that has slowly but surely lost its structure and elasticity. They do this by promoting collagen production.
- Calming inflammation: Free radicals can take a toll on your skin. Exosomes naturally gravitate to inflamed tissue, where they deliver anti-inflammatory compounds. Right where your skin needs them most.
What makes Exosome skincare products particularly intriguing is they don’t just have Exosomes in them. Formulas here at Naturopathica contain other professional botanical ingredients to maximize results.
How to Use Exosomes in Skincare: Step-by-Step Guide to Elevating Your Ritual
It’s actually quite easy to incorporate Exosomes into your skincare ritual. You just need to pick the right products and understand proper layering. Here’s how to use Exosomes in skincare.
Choosing the Right Formula
There are two wonderful Exosome products in store for you at Naturopathica, and both belong in your ritual if you’re serious about harnessing the potential of these little messengers.
Our Gotu Kola + Fruit Exosome Rejuvenating Essence is a water-light formula that penetrates deeply into the skin after cleansing. It pushes fruit-based Exosomes and Gotu Kola into the skin as the first hydration step in your ritual.
The Gotu Kola + Fruit Exosome Gel Moisturizer is a deeply hydrating gel formula. Yet it’s still relatively lightweight compared to cream-based moisturizers, so it doesn’t feel “heavy” on the skin. It absorbs seamlessly and leaves no trace behind, other than a wonderful cooling sensation. This product locks Exosomes in and calms stressed skin with lasting moisture.
We recommend having both in your regimen.
Proper Layering Practices
Exosomes are just one piece of the puzzle. Here’s when to use Exosomes in skincare alongside the rest of your ritual:
- Step 1) Cleanse: You need a clean base for Exosomes to work their magic. Remove makeup, sunscreen, and daily buildup using our Calendula Essential Cleansing Oil or Manuka Honey Cleansing Balm.
- Step 2) Exosome Essence: Dispense a little essence onto a cotton pad and sweep over your face, neck, and chest. Do not rinse. Feel it sink into your pores.
- Step 3) Serum (optional): Your choice of serum depends on what your skin needs most. Maybe it’s our Plant Stem Cell Booster Serum. You may not even use a serum.
- Step 4) Exosome Gel Moisturizer: Smooth the formula over your face and neck to seal in everything you applied first. You’ll feel a delightful cooling sensation, and you’ll know the Exosomes are working to support skin at the cellular level.
- Step 5) SPF (morning only): Not necessary at night. But if you use Exosomes as part of your morning ritual, be sure to apply SPF before leaving home.
Some people break up their Exosome skincare products - Essence in the morning, Gel Moisturizer at night before bed. When to use Exosomes in skincare is up to you. The layering order is what matters most (lightest to heaviest).
Using Exosomes At-Home vs in a Clinical Setting
Our advice is always to learn how to use Exosomes in skincare topically. But you may see people swear by the idea of injectable Exosomes, or post-procedure Exosome treatments. There are some important distinctions here as far as safety and results go.
Topical Exosomes deliver vital signaling molecules straight through the skin’s surface. They’re accessible - no needles, clinic visits, expensive bills, or recovery time. And they flat out work. We have clinically proven data for our Exosome skincare products showing they can:
- Enhance skin hydration levels by over 1.5x immediately after use
- Improve the look of fine lines & wrinkles
- Boost skin elasticity
100% of customers said their skin felt instantly hydrated, refreshed, and more comfortable. They also said their skin looked smoother, more supple, and firmer.
In a clinical setting, some practitioners will offer injectable Exosomes or apply Exosome solutions after microneedling, hoping to push them deeper into the skin than they already go.
Board-certified dermatologist Dr. Olga Bachilo says, “There are no exosome products currently on the market that are FDA-approved for injections.”3 This is just one reason we don’t recommend any sort of injectable Exosome protocol.
Every formula at Naturopathica is developed and tested by estheticians in our own spas before they ever reach your shelf. We also use fruit-based Exosomes because they’re far gentler and don’t have the same concerns as those derived from stem cells.
So if you want to learn how to use Exosomes in skincare with peace of mind, look no further.
Tap Into the Benefits of Exosome Skincare Today
We’ve developed botanical formulas in our own treatment rooms for more than 30 years, always practicing the right balance of ancient botanical wisdom with modern skincare science. That same standard shines through in our clinically proven Exosome skincare line.
Now that you know how to use Exosomes in skincare, the next step is choosing the right products for your ritual. Whether you begin with the Rejuvenating Essence, the Gel Moisturizer, or both, give your skin what it needs to look and feel renewed.
Frequently Asked Questions
Do exosomes in skincare actually work?
Yes. They deliver vital growth factors and signaling proteins that support cell repair, hydration, and firmness. Our products are backed by clinical results and countless user reviews.
When do you use exosomes in skincare?
Depends on the format. Exosome essence should be used right after cleansing. Exosome moisturizer comes after serums as the final step (other than SPF) to seal everything in. Use Exosomes daily for best results.
Are the results of exosomes permanent or temporary?
Temporary, which is why consistent use is critical. You cannot skip days and expect to maintain results. Make Exosomes a non-negotiable part of your skincare ritual.
How often can you use exosomes on face?
Daily. Morning and/or evening. They are well-tolerated and gentle enough for twice-daily use.
Can you use exosomes and retinol together?
You can, and perhaps should. Exosomes support essential repair and hydration processes, while Retinol encourages faster cell turnover to help reveal fresher, healthier-looking skin. You can apply Retinol at night and Exosomes in your morning ritual.
What not to do after exosomes?
Don’t rinse anything off. Do not use physical scrubs or strong acid exfoliants. You don’t want to do anything that will interrupt the Exosomes as they’re doing their thing.
What is the most effective exosome serum?
You want a formula featuring fruit-derived Exosomes AND proven botanical extracts, which is what makes Naturopathica’s line the #1 choice. You get targeted skin renewal and hydration in a single product.
When is it time to add exosomes to my skincare ritual?
Don’t wait. Start tapping into the benefits of Exosome skincare today and see for yourself why people are raving about these products from Naturopathica.
Related Resources
How to use Manuka Honey on face | Argan Oil benefits for skin | Exosomes vs Peptides
